Currently we are recruiting adults with Atopic Dermatitis and NASH (Nonalcoholic Steatohepatitis) who would like to assist in clinical studies that investigate the properties of medications designed to help relieve the symptoms of these conditions.
If you have one of these conditions and are interested in participating in clinical research, call one of our recruitment offices today.
Atopic dermatitis (a common type of eczema) is a condition that makes your skin red and itchy. Atopic dermatitis is long lasting (chronic), tends to flare periodically, and may be accompanied by asthma or hay fever.
Atopic dermatitis signs and symptoms vary from person to person and can include:
If you have ATOPIC DERMATITIS and are interested in participating in clinical research, call one of our recruitment offices today.
NonAlcoholic SteatoHepatitis (NASH) is liver inflammation and damage caused by a buildup of fat in the liver. It is part of a group of conditions called NonAlcoholic Fatty Liver Disease (NAFLD). NAFLD is a condition in which fat builds up in your liver, commonly called "fatty liver." If you have NASH, you likely have inflammation and liver cell damage, along with fat in your liver.
Normally, NASH exhibits few or no symptoms; however, certain health conditions -- including obesity, metabolic syndrome and type 2 diabetes -- make you more likely to develop NAFLD and NASH.
If you have NASH and are interested in participating in clinical research, call one of our recruitment offices today.
TOPICAL/SKIN: These types of studies test topical (applied to the skin surface) corticosteroids (e.g., hydrocortisone). Corticosteroid products cause blanching (whitening) of the microvasculature (very small blood vessels) of the skin. This blanching response is thought to be related to the amount of drug entering the skin. Participants in these studies will have test drug products (e.g., lotions, ointments, creams or tapes) applied to their forearms for specific amounts of time and then the products will be removed. The blanching responses will be measured using a device called a chromameter (color measurement) at regular intervals during the study. Participants will usually stay at Novum two overnights during these studies, and they do not normally require any blood collections.
PK-BIOEQUIVALENCE: These types of studies typically compare two drug products, for example, a commercially available Brand product (e.g., Tylenol®) and a potential to-be-marketed generic product (e.g., acetaminophen). Pharmacokinetic (PK) studies are usually performed in which each of the drug products is administered in a cross-over design (each participant will receive each drug product separately over the course of the study) to volunteer participants who are in general good health. After receiving a drug product, blood samples are taken at regular intervals and then tested for the drug concentration. For these types of studies, participants will usually stay at Novum on two separate occasions for two overnights on each occasion. Sometimes, there may be return visits required for additional drug concentration blood collections after being released from the clinic.